Hepatic Studies

1. Evaluation of single and multiple dose pharmacokinetics of XXX in subjects with moderate hepatic insufficiency.
2. A single oral dose pharmacokinetic study of XXX in healthy subjects and subjects with mild to severe hepatic impairment.
3. Steady-State Stereospecific pharmacokinetics of XXX HCL extended release tablets in patients with mild and moderate hepatic impairment.
4. Safety and pharmacokinetic study of XXX in subjects with normal or impaired hepatic function.
5. Evaluation of the safety and pharmacokinetics of XXX following administration of a single dose of XXX to subjects with moderate chronic hepatic insufficiency.
6. Open-label evaluation of the single dose pharmacokinetics of XXX in subjects with and without hepatic impairment.
7. A phase I randomized, placebo-controlled, double-blind, multiple (ascending) dose study of the safety and pharmacokinetics of XXX compound XXX in subjects with Hepatitis C Virus infection.